NEXT GENERATION EU
KEY ENABLING TECHNOLOGIES

NEUROCLIMA: raising awareness on climate resilience strategies

NEUROCLIMA, a project coordinated by Professor Francesca Rizzo of the Department of Design at Politecnico di Milano, has kicked off; it is granted by the CINEA – European Climate, Infrastructure and Environment Executive Agency within the Horizon Europe framework programme.

NEUROCLIMA aims to promote and support systemic transformations by involving and raising awareness among citizens regarding climate resilience strategies. The project envisions the creation of a nervous system that connects policymakers, public institutions, and citizens through an innovative mixed decision support system that combines artificial intelligence and human capabilities.

By conducting in-depth research to identify needs, challenges, expectations, and trends that may influence EU societies, and a continuous dialogue among stakeholders, the goal is to develop concrete proposals to facilitate the green transition and enhance trust in institutions.

Improving sustainability and safety of critical infrastructures with AI

Using Artificial Intelligence (AI) to support decision-making, and increasing efficiency and safety in the operation of critical infrastructures. This is the aim of the European project AI4REALNET – AI for REAL-World network operation, funded by the European Union with almost 4 million euros, through the Horizon Europe programme, and by the State Secretariat for Education, Research and Innovation (SERI) of Switzerland with 2 million euros.

The project, led by the Portuguese research institute INESC TEC, involves the Department of Electronics, Information and Bioengineering, and the Department of Management, Economics and Industrial Engineering of the Politecnico di Milano, and partners from France, Germany, Netherlands, Swizterland, Sweden and Austria, and promotes the collaboration between Artificial Intelligence and humans. The aim is to ensure that AI emerges as a way to support faster decisions made by human operators, creating conditions for the decarbonisation of the energy and transport sectors.

The project aims at improving the safety and resilience of critical infrastructures, which are becoming more challenging, not only due to the increase in the volume of information, but also due to the changes imposed by decarbonisation. The AI4REALNET consortium

Prof. Marcello Restelli, project coordinator for the Politecnico di Milano

With the involvement of industry, the project will promote awareness of the benefits of reinforcement learning and explainable machine learning. The project will also resort to current open-source AI-friendly digital environments, e.g., Grid2Op, Flatland, and BlueSky to foster and advance a global AI community.

ACRE, agricultural robots to contribute to the sustainability of the sector

Politecnico di Milano took part in the second edition of ACRE (Agri-food Competition for Robot Evaluation), a competition dedicated to agricultural robots, which took place in Cornaredo (MI) at the ‘Cascina Baciocca’ experimental farm of the University of Milan.

This edition of ACRE was dedicated to robots designed for the weeding of open-field crops, an area in which exploiting this type of machine, even in a low-cost version, could bring great environmental, social and economic benefits by providing an alternative to the use of chemicals.

The competition involved robots built both by start-ups connected in various ways to academia and developing advanced robotic solutions and by companies already offering engineered products on the market. The performances were evaluated according to strict scientific criteria predefined by the organisers with the aim to measure the performance of all participants in an objective and repeatable manner.

ACRE’s main goal is to bring the world of agricultural machinery industry closer to the world of expert researchers in the field of robotics and artificial intelligence, in order to also create solid partnerships that in the near future will allow bridging the existing agricultural robotics gap between the European industry and that of the United States – and similarly between the Italian industry and that of various European realities such as the Netherlands and France.

ACRE is funded by the European Commission as part of the Horizon 2020 ‘METRICS’ project, with the primary aim of increasing the spread of robots and artificial intelligence techniques in agriculture. The competition is organised on the Italian side by AIRlab, the Artificial Intelligence and Robotics laboratory of Politecnico di Milano, and by the Department of Agricultural and Environmental Sciences of the University of Milan, with the collaboration of FederUnacoma and Informatore Agrario.

TROPHY project kicks off

Activities related to the TROPHY (ulTRafast hOlograPHic FT-IR microscopY) project have officially started. TROPHY is a research project, funded by the European Commission under the Horizon Europe programme, which aims to develop a novel label-free vibrational microscopy approach for cancer diagnosis.

Cancer diagnosis is traditionally done on intraoperative frozen tissue sections by post-surgical histopathologic analysis and, in selected cases, by elaborated and time-consuming molecular diagnosis. The analysis of the biopsy is performed through the staining of the tissue and the evaluation of the morphology of its cells under an optical microscope. This approach is neither fast nor quantitative, has an intrinsic variability in the interpretation depending on the experience of the histopathologist, and provides limited molecular information.

The microscope developed thanks to the TROPHY project will image molecular biomarkers with unprecedented speed and chemical selectivity for a rapid, precise, and non-biased tumor analysis. To this purpose, it will blend in a unique fashion elements of several microscopies developed in the past decades, namely photo-thermal infrared, Fourier transform infrared and Digital Holography Microscopy, bringing them to the unprecedented ultrafast timescale. It will also integrate Artificial Intelligence to produce fast results and assist in the tumour grading process even during surgery.

This microscope will be used to assist healthcare professionals during tumor biopsy diagnostics, provide an accurate diagnosis for curative oncosurgery, guarantee complete resection during intervention, determine the best therapeutic approach tailored to the patient, and identify resistant tumor clones under targeted therapy, paving the way for continual precision medicine in cancer.

The project is coordinated by the Politecnico di Milano with Prof. Marco Marangoni from the Department of Physics as scientific coordinator. The other project partners are Fundacio Institut de Ciences Fotoniques (ICFO, Spain), Consiglio Nazionale delle Ricerche (CNR, Italy), Lyncee Tec SA (LT, Switzerland), Universtaetsklinikum Jena (JUH, Germany), University of Exeter (UNEXE, UK), University of Cambridge (UCAM, UK).

AI-based personalized medical care for lung cancer patients

I3LUNG is a new research initiative that aims to create a cutting-edge decision-making tool to aid both clinicians and patients in selecting the best lung cancer treatment plan, tailored to the specific needs and situation of each individual patient.

Lung cancer was the leading cause for cancer deaths in men and the second for women in 2020, with 370000 deaths in Europe alone. The consortium has thought out and developed this project to address the primary unmet clinical need in the field of non-small cell lung cancer (NSCLC), which is the lack of biomarkers predicting the response of affected patients to immunotherapy (IO)-based treatments.

The project will use artificial intelligence (AI), in particular deep and machine learning methodologies (DL and ML) to analyze a wide range of information such as baseline clinical features, radiomics, and available biological characteristics of the tumor.

I3LUNG and its partners will have a timeframe of 5 years and a €10M budget to turn their project’s hypothesis in a tangible tool and a new clinical reality. I3LUNG is the first platform enrolling such an important number of patients in both a retrospective (2,000) and prospective (200) manner including such a diversity of multiomic data, arising as an innovative and promising technology to provide an answer to the unmet clinical need of translational research data integration and AI use.

This project is envisioned to both generate novel therapeutic guidelines for clinical practice in lung cancer and support the growth of digital diagnostic tools. AI will push the standard of care towards a more personalized approach for each individual cancer patient. If successful, the approach presented in I3LUNG could in the near future be extended to other cancer types.

The team of the Politecnico di Milano, which combines computer science and biomedical engineering experts, aims to study together with medical partners if and how Artificial Intelligence can become an actor in the complex path of therapy selection. The goal is to develop artificial intelligent solutions that are not only capable of accuracy and precision, but also an understandable interlocutor, at the service of clinical experts, their knowledge and experience and worthy of trust for patients.

Prof. Alessandra Pedrocchi of the Department of Electronics, Information and Bioengineering, project coordinator for our university

The partners in the consortium I3LUNG are: 

  • Fondazione IRCCS Istituto Nazionale dei Tumori(INT, Milano, Italia) with Dr Arsela Prelaj as coordinator of the Consortium
  • Politecnico di Milano(POLIMI, Milano, Italia)
  • Istituto di Ricerche Farmacologiche Mario Negri (IRFMN, Milano, Italia)
  • Istituto Europeo di Oncologia (IEO; Milano, Italia)
  • ML Cube(Milano, Italia)
  • LungenClinic Grosshansdorf GmbH (GHD, Grosshansdorf, Germania)
  • Universitaetsklinikum Hamburg-Eppendorf (UKE, Amburgo, Germania)
  • Vall d’Hebron Instituteof Oncology (VHIO, Barcellona, Spagna)
  • Medica Scientia Innovation Research (MEDSIR, Barcellona, Spagna & New Jersey, USA)
  • Metropolitan Hospital (MH, Pireo, Grecia)
  • Shaare Zedek Medical Center (SZMC, Gerusalemme, Israele)
  • Katholieke Universiteit Leuven (KUL, Leuven, Belgio)
  • Institutet for Halso-OCH Sjukvardsekonomi Aktiebolag (IHE, Lund, Svezia)
  • University of Chicago (UOC, Chicago, USA)
  • Aalborg Universitet (AAU, Aalborg, Danimarca)
  • Lung Cancer Europe (LUCE, Bern, Svizzera)

Photons to create an artificial quantum neuron

A group of researchers of the Department of Physics at the Politecnico di Milano, the National Research Council (CNR) and the University of Vienna, have developed a device, called a quantum memristor, which could combine artificial intelligence and quantum computing.

This is an advance that can open up as yet unseen potential, allowing to employ the very high computational power guaranteed by quantum technologies in the fields of application of artificial intelligence, which already range from automatic speech interpretation to face recognition, from medical diagnostics to autonomous driving.

Artificial intelligence algorithms are based on mathematical models called neural networks, inspired by the biological structure of the human brain, which is made up of interconnected nodes (neurons). One of the fundamental components of neural networks is the memristor (or memory-resistor), a component that changes its electrical resistance based on a memory of the current that passed through it, in a way that is surprisingly similar to that of neural synapses, i.e. the connections between neurons in the brain.

The group of experimental physicists led by Roberto Osellame (CNR) has shown that it is possible to engineer an optical device with the same functional characteristics as the memristor, capable of operating on quantum states of light and thus encoding and transmitting quantum information: a quantum memristor.

We also simulated an entire optical network made up of quantum memristors, showing that it could be used to learn both classical and quantum tasks.

Andrea Crespi, professor of Experimental Physics at the Politecnico di Milano

This result seems to suggest that the quantum memristor may be the missing link between artificial intelligence and quantum computing, unleashing the potential of quantum resources within artificial intelligence applications.

The study received the cover of the April issue of Nature Photonics magazine.

© photo: Equinox Graphics

Satellites and artificial intelligence to study fine dust

Climate and extensive anthropisation of the area make the Po Valley one of Europe’s most polluted regions, despite emissions being actually comparable to those of other industrialised districts. Particulate matter, or fine dust, heads the list of the most critical polluting agents.

Long-term exposure to high concentrations of particulate matter increases the incidence of both cardiovascular and respiratory diseases. Industries, traffic and domestic heating are some of the leading sources of fine dust emissions. However, even intensive livestock breeding and agricultural activities can contribute to the dissemination of this harmful pollutant. To date, few studies have been conducted on the topic.

The D-DUST project (Data-driven moDelling of particUlate with Satellite Technology aid) aims to bridge this gap by providing important data to investigate the impact of emissions from agricultural and livestock activities on our health. D-DUST, funded by Fondazione Cariplo’s ‘Data Science for Science and Society’ call for proposals, counts on Politecnico di Milano, Department of Civil and Environmental Engineering (DICA) as lead partner, in partnership with Fondazione Politecnico di Milano, the Department of Electronics, Information and Bioengineering (DEIB) and Università degli Studi dell’Insubria (DiSAT) as scientific partners.

Maria Antonia Brovelli, our Geographical Information Systems professor who is coordinating the project, explained that

the D-DUST project will test new analytical and predictive procedures for the generation and diffusion mechanisms of particulate matter from the agricultural sector. These procedures are solely based on the vast wealth of environmental data and observations now available as open data, with particular focus on the potential contribution of new satellite missions designed to monitor air quality.

The study will also make use of the Sentinel satellite platforms of the European Copernicus programme, including the Sentinel 5P satellite, which provides open data measurements of the main atmospheric pollutants on a global scale, together with the study of spatial predictive models based on machine learning techniques. Models will be developed taking into account data from the fixed ground-based monitoring stations of the ARPA Lombardy network, and data from the detection and chemical characterisation campaigns of particulate matter combined with data on the incidence of cardiovascular and respiratory diseases. Professor Brovelli further emphasises that

the research aims to increase local knowledge of particulate matter even in areas not covered by ground-based measurement stations, in order to provide estimates and forecasts that could be replicated and used to monitor and analyse population exposure to this pollutant.

In parallel to the research described above, educational activities will be organised, mainly involving students from agricultural senior high schools through awareness-building workshops and direct participation in monitoring campaigns. The project will also involve non-profit organisations and foundations actively participating in research, education and dissemination projects on environmental issues.

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