Technology can do a great deal to improve our responses to the challenges of a complex interconnected society. We also have an urgency to tackle the economic, social and cultural threats and tools of the technological transformations. Researchers at Politecnico di Milano address these challenges from several different perspectives that include safeguarding and promotion of cultural heritage and cultural, designing strategies for inclusive growth, supporting politics and governance in a post pandemic world, with the goal to drive the transition towards sustainable, inclusive society.